Heart & Kidney Health

Clinical trials are enrolling to learn about the effect of an investigational weight-loss medication on heart and kidney function.

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Therapy area Heart & Circulation

The heart pumps around 7,500 litres of blood every day. The kidneys filter waste and excess fluid from around 170 litres of that blood – Every. Single. Day.

That’s a lot of work.

Paying attention to heart and kidney health is key to well-being. Common health conditions can stress both organs and threaten their ability to do their job.

Excess weight is one of these conditions. Being overweight can lead to risk factors for chronic kidney disease (CKD) and cardiovascular disease (CVD). Some of these risk factors include:

  • High blood pressure
  • High cholesterol
  • High blood sugar
  • Type 2 diabetes
  • Fatty liver disease

Currently, doctors and specialists are leading research studies to learn about the effect of investigational weight-loss medication on heart and kidney function. They’re looking for study volunteers who have weight-related risk factors for CKD or CVD (the bulleted list above includes just a few of the most common), or who have been diagnosed with either disease. Being overweight or having obesity can affect how fast and aggressively these diseases may progress.

See if you are eligible today.

  • You will be compensated – £X per visit for your time and inconvenience in addition to travel expenses.

All Synexus clinical trials are conducted under the supervision of an independent ethics committee and the Medicines and Healthcare Products Regulatory Agency (MHRA)

“From my very first visit, I have experienced friendly, helpful and knowledgeable staff in all aspects. The work they do makes a difference. Excellent all-round performance and advice, if and when needed.”

– Keith Butterworth, Synexus clinical trial participant

Everything you need to know

Clinical trials are medical research studies that test investigational medicines and treatments. People may not give much thought to clinical research, but everything from aspirin to chemotherapy has been carefully tested before being prescribed by your doctor.


Clinical trials need human volunteers, who participate under the supervision of a doctor and/or health professionals. As the trial goes on, the doctors gather more and more information about the medicine or treatment under investigation. It is only through clinical trials that we learn if medicines and treatments are both effective and safe.