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Proud to be the patient’s choice for clinical research

Dedicated to conducting clinical trials, Synexus have been investigating the effectiveness of new medicines and treatments for more than 25 years. We have vast experience in conducting clinical research with 7 clinics in the UK and approaching 200 sites around the world. Each has its own dedicated team of highly trained doctors and nurses to provide our patients with the highest level of comfort and professionalism.

Whether discussing your progress over a cup of tea or enjoying complimentary snacks after fasting for a blood sample, these personal touches make Synexus clinics such a welcoming place for you to take part in a clinical trial.

Browse all clinical trials

Bones & Joints

Bones and joints are part of our musculoskeletal system and they provide the framework for the body to move. Bones and joints may be affected by painful conditions such as arthritis, osteoporosis, tendonitis and rheumatoid arthritis.

The most common condition affecting bones is osteoporosis which is caused by a reduction in bone mass. Losing bone mass is a natural part of aging however it may be excessive in some people who end up developing osteoporosis. This means your bones become weak and are more likely to have fractures and damage.

We regularly conduct clinical trials into osteoporosis or studies evaluating the risk of developing osteoporosis, as well as clinical trials for arthritis. Our state of the art DEXA scanning machines help with the accurate diagnosis of osteoporosis and monitoring of patients who are at risk of developing osteoporosis.

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Chronic Pain

Pain is a severe sensory experience which may affect any part of the body. It may be acute pain which lasts for a short period of time but is often severe such as headaches, or it may be chronic (or persistent) pain which lasts for weeks, months or even years such as back pain. Chronic or persistent pain is defined as pain that has lasted for longer than three months after the usual recovery period for an illness or injury.

We regularly conduct clinical trials into chronic pain treatment which includes conditions such as headache and migraine, back, shoulder, knee or neck pain. We also conduct studies in pain related to post dental surgery, shingles (herpetic neuralgia) and diabetes as well as pain that occurs after an injury or operation.

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Diabetes mellitus is a condition in which your blood sugar levels are too high because the body cannot control the level properly. Insulin is a hormone that is produced by the pancreas and lowers blood sugar by helping the sugar (glucose) to move into your body cells which use it as a source of energy.

There are different types of diabetes: Type I diabetes occurs when your pancreas does not make any insulin and may be diagnosed in childhood or early teens. Type 2 diabetes occurs when your pancreas is unable to make enough insulin or it no longer works effectively to reduce blood sugar levels. High levels of blood sugar can cause serious problems which may damage your eyes, kidneys, and nerves.

We regularly conduct clinical trials involving Type2 diabetes to reduce the blood sugar levels, reduce the risk of heart attacks and strokes and problems that can arise as a result of high blood sugar levels.

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Digestion & Bowel

Problems affecting the digestion and bowel are very common and may cause severe pain, weight loss, change in bowel motion and abdominal discomfort. The most common digestive problems such as heartburn, reflux, peptic ulcers, inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) cause daily suffering for millions and can limit a person’s quality of life.

We regularly conduct clinical trials for conditions such as reflux, indigestion, peptic ulcers, constipation, diarrhoea and irritable bowel syndrome.

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Endocrine & Metabolism

The endocrine system is a network of glands that produce and release hormones. Hormones are chemical messengers that travel through your bloodstream to tissues and organs. Hormones help to control many important bodily functions and affect nearly every cell and organ in the body. They affect the body’s ability to produce the energy that is needed to power cells, they stimulate cell growth and development, affect your mood, strengthen bones, influence sexual functions and control your metabolism. There are many different types of hormone disorders and diabetes is an example of an imbalance in insulin.

We regularly conduct clinical trials for conditions such as diabetes, as well as studies into obesity, osteoporosis, high cholesterol and lipids, and other metabolic disorders.

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Heart & Circulation

The heart and circulatory system delivers blood to every cell in our body through a network of blood vessels. Problems to the blood vessels are common and can result in high blood pressure, poor circulation (peripheral arterial disease), atherosclerosis which is where the wall of the artery becomes thickened.

The most common cause of heart disease is narrowing or blockage of the coronary arteries, the blood vessels that supply blood to the heart itself and is the reason that most people have a heart attack. You are more likely to have problems with your blood vessels as you get older.

We regularly conduct clinical trials for conditions such as high cholesterol, high blood pressure and diseases that put you at a greater risk of having a heart attack/stoke or a recurrence of these events. We will normally conduct an evaluation of your lipid profile as part of a cardiovascular study evaluation.

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Immunology & Vaccination

The human body has numerous mechanisms to fight infection. The immune response is how your body recognizes and defends itself against bacteria, viruses, and substances that appear foreign and harmful. In most cases, the immune response will keep you healthy and will prevent infections. But sometimes problems with the immune system can lead to infections, allergies or diseases such as Lupus.

To help prevent infection scientists have developed many vaccines for specific diseases such as whooping cough, measles and polio. Vaccines work by stimulating our immune system to produce antibodies (substances produced by the body to fight disease) without actually infecting us with the disease. This helps to prevent us from getting the infection in future.

We regularly conduct clinical trials for allergy as well as vaccine studies for the prevention of many diseases.

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We regularly conduct research studies relating to lifestyle and habit, such as weight management, smoking cessation, nutritional supplements.

Many of our studies involve ongoing support in relation to diet, counselling, and exercise.

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Mind, Mood & Memory

Your brain stores information and when you remember something, you pull the information from your memory. But your memory doesn’t always work perfectly. As people grow older it may take longer to remember something and it is normal to forget things. Older people who become more forgetful than others of their age may have “mild cognitive impairment”.

Forgetting how to use the telephone or find your way home may be signs of a more serious problem, such as Alzheimer’s disease or other types of dementia, stroke, depression, head injuries, thyroid problems, or reactions to certain medicines.

We regularly conduct clinical trials into cognitive changes (trouble remembering, learning new things, concentrating, or making decisions), sleep disturbances, dementia, addiction and mental and emotional health issues such as depression. We will normally conduct an evaluation of your memory as part of our memory study evaluation.

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Reproduction & Women's Health

Reproduction is the process by which people have children. There are many conditions which may affect the male reproductive system and that may be part of a Synexus clinical trial including erectile dysfunction, contraception, sexually transmitted diseases, and conditions affecting the prostate gland such as an enlarged prostate gland and screening for prostate cancer.

Disease and conditions that affect the female reproductive system or women’s health include contraception, menstruation, and post-menopausal conditions and sexually transmitted diseases.

We regularly conduct clinical trials for female sexual dysfunction, menstrual and post menopause-related conditions as well as many aspects of women’s health.

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Breathing is controlled by the respiratory system and when you breathe you take in oxygen and get rid of carbon dioxide. Many conditions related to the health of your lungs can result in shortness of breath, chronic coughing or breathing difficulties. The short term problems are usually caused by infections, such as colds and flu but long term breathing problems may be due to medical conditions such as allergies, asthma and COPD.

We regularly conduct clinical trials into breathing problems such as Asthma and COPD as well as treatments for smoking cessation and flu vaccinations. We routinely use spirometry tests (breathing tests) to determine how well your lung is functioning as part of the assessment before you participate in a study.

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Skin Conditions

Your skin is your body’s largest organ its role is to cover and protect your body.

As well as covering for your internal organs, your skin helps you to feel the external environment, for example, hot, cold and pain and is important in making vitamin D when the sun shines. Anything that irritates, clog or inflames the skin can cause symptoms such as redness, swelling, burning or itching. In addition, you can get allergic reactions that show themselves as rashes or other skin conditions. There are many different skin disorders. Some are short term, easily treated, and just a nuisance. Others can persist for a long time and be troublesome and many skin problems, such as acne or atopic dermatitis (eczema) affect your appearance.

We regularly conduct clinical trials into skin conditions, including atopic dermatitis (eczema), acne, rosacea, and psoriasis.

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What’s involved?

Our informed consent process is designed to help give you all the information that you need as well as an opportunity to ask questions and decide what is right for you.

Our team will talk through your current health and advise you about any clinical trial you might be suitable for. If you want to go ahead, we will arrange a consultation at one of our clinics to give you full study details to take away and discuss with your family before you make a decision.

Why take part?

You’ll be joining a growing community of over 14,000 Synexus volunteers.

Our highly trained doctors and nurses provide an advanced level of comfort and care.

You will receive a free health check and be contributing to the health of future generations.

We can help with transport to and from our clinics or reimburse for reasonable travel expenses.

How do I take part?

We have put together a guide to help you better understand our clinical trials and determine whether they are the right option for you.

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Refer a friend

If you know somebody who may be suitable for a clinical trial, please recommend them to Synexus and you’ll receive £100 as a thank you when they enrol on a study.

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