Fatty Liver Disease

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Therapy areas Diabetes Digestion & Bowel

An estimated 20-30% of the UK population has non-alcoholic fatty liver disease. For those with NASH, no medication is available to reverse the fat build up in the liver and the disease may continue to progress.

  • We are looking for volunteers to take part in clinical trials to better understand the condition and help find new treatments.
  • Appropriate volunteers will receive a free fibroscan, a procedure that helps assess the damage in the liver and not always available on the NHS.
  • Eligible participants will also receive a free health check and Synexus can help with transport to and from one of our clinics, or reimburse reasonable travel expenses.

All Synexus clinical trials are reviewed an independent ethics committee and the Medicines and Healthcare Products Regulatory Agency (MHRA)

To enable us to assess your suitability for upcoming clinical trials please:

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0800 880 7001

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0800 880 7001

Are You at Risk for Fatty Liver?

Being at risk for NASH can be linked to a number of health factors. To see if you may be at risk and discover your next step, please enter the information below.


NASH risk increases with age.


People with a high BMI are at higher risk of developing NASH.

Pre-diabetes or Diabetes?

Having insulin resistance is linked to a higher risk of having NASH.

Blood Pressure

People with elevated blood pressure may be at risk of developing NASH.


People with elevated cholesterol may be at risk of developing NASH.

Everything you need to know

As one of the largest and most recognised clinical trial organisations in the world, Synexus provides a friendly relaxed environment where you have the opportunity to help others and maybe also yourself. A clinical trial offers an opportunity to help researchers find better treatments for others in the future.

If you have the following risk factors, you may be eligible to participate in a clinical trial:

  • Type 2 diabetes
  • Obesity
  • High blood pressure OR high cholesterol

It is a scan similar to an ultrasound used during pregnancy which will measure how elastic (or how stiff) your liver is. A healthy liver should be soft and elastic, and if your liver is stiff this is a sign that some damage has occurred.

How is it done?

It is a painless procedure which involves a probe being passed over the top right area of your stomach.

Your Fibroscan will be carried out at an outpatient clinic appointment.

What are the benefits?

The results of the scan can help your doctor find out about the level of damage that affects your liver, and decide what treatment you might need.

It is helpful for measuring the degree of liver damage in people with:

  • Viral hepatitis B and C
  • Alcoholic liver disease
  • Non-alcoholic fatty liver disease
  • Hepatitis C and HIV co-infection
  • Haemochromatosis (iron overload disorder)
  • Other liver diseases
  • What are the risks?

There are no risks involved. It is painless and not invasive (meaning it’s not carried out inside your body and does not break the skin).