Major Depression

Be part of clinical trials. Do something rewarding.

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Therapy area Mind, Mood & Memory

Major Depressive Disorder (MDD) affects approximately 300 million people worldwide. It is the leading cause of disability across the globe. In Europe alone, 44.3 million are coping with MDD. Symptoms include feelings of hopelessness, overwhelming guilt, and loss of interest in activities. Sleep problems—either the inability to fall asleep or stay asleep—are especially common and can lead to worsening depression.

  • We are looking for volunteers to take part in clinical trials to understand the condition and help find new treatments.
  • Eligible volunteers who choose to participate may receive no-cost study medication and clinical trial-related care.
  • Synexus can also help with transport to and from one of our clinics or reimburse reasonable travel expenses.

All Synexus trials are approved by an independent ethics committee.

To enable us to assess your suitability for upcoming clinical trials please:

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0800 470 2437

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0800 470 2437

COVID-19 update — we remain open.

For the safety of both staff and patients, we require that our research sites are COVID-19 SMART facilities. That means they use best practices to reduce virus exposure and are dedicated to ensuring they remain open and available for the research of investigational medications.

COVID-19 SMART steps we are taking to ensure safety include:

  • Greatly increased availability of video office visits
  • Ensuring social distancing measures are taken in all waiting areas
  • Continuing the practice of cleaning and disinfecting exams rooms thoroughly between every patient visit
  • Appropriate personal protective equipment (PPE) for all staff members at our health clinics

Everything you need to know

As one of the largest and most recognized clinical trial organizations in the world, Synexus provides a friendly relaxed environment where you have the opportunity to help others and maybe also yourself. Clinical trials offer an opportunity to help researchers find better treatments for others in the future.

All Synexus studies are approved by an independent ethics committee.

If you have the following risk factors, you may be eligible to participate in a clinical trial:

  • Diagnosis of Major Depressive Disorder
  • Inadequate response to current antidepressant therapy with an SSRI or SNRI
  • Male or female, 18 years of age or older